diff --git a/CHANGELOG.md b/CHANGELOG.md
index bc4783a..0fe327c 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -7,6 +7,89 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 
 ## [Unreleased]
 
+### ✨ Enhancements
+
+**Issue #361: Enhanced HTTP Request Node Validation Suggestions**
+
+Added helpful suggestions for HTTP Request node best practices to prevent common production issues discovered through real-world workflow analysis.
+
+#### What's New
+
+1. **alwaysOutputData Suggestion**
+   - Suggests adding `alwaysOutputData: true` at node level (not in parameters)
+   - Prevents silent workflow failures when HTTP requests error
+   - Ensures downstream error handling can process failed requests
+   - Example suggestion: "Consider adding alwaysOutputData: true at node level for better error handling. This ensures the node produces output even when HTTP requests fail, allowing downstream error handling."
+
+2. **responseFormat Suggestion for API Endpoints**
+   - Suggests setting `options.response.response.responseFormat` for API endpoints
+   - Prevents JSON parsing confusion
+   - Triggered when URL contains `/api`, `/rest`, `supabase`, `firebase`, `googleapis`, or `.com/v` patterns
+   - Example suggestion: "API endpoints should explicitly set options.response.response.responseFormat to 'json' or 'text' to prevent confusion about response parsing"
+
+3. **Enhanced URL Protocol Validation**
+   - Detects missing protocol in expression-based URLs
+   - Warns about patterns like `=www.{{ $json.domain }}.com` (missing http://)
+   - Warns about expressions without protocol: `={{ $json.domain }}/api/data`
+   - Example warning: "URL expression appears to be missing http:// or https:// protocol"
+
+#### Investigation Findings
+
+This enhancement was developed after thorough investigation of issue #361:
+
+**Key Discoveries:**
+- ✅ Mixed expression syntax `=literal{{ expression }}` **actually works in n8n** - the issue report's primary claim was incorrect
+- ✅ Real validation gaps identified: missing `alwaysOutputData` and `responseFormat` checks
+- ✅ Workflow analysis showed "?" icon in UI caused by missing required URL (already caught by validation)
+- ✅ Compared broken vs fixed workflows to identify actual production issues
+
+**Testing Evidence:**
+- Analyzed workflow SwjKJsJhe8OsYfBk with mixed syntax - executions successful
+- Compared broken workflow (mBmkyj460i5rYTG4) with fixed workflow (hQI9pby3nSFtk4TV)
+- Identified that fixed workflow has `alwaysOutputData: true` and explicit `responseFormat: "json"`
+
+#### Impact
+
+- **Non-Breaking**: All changes are suggestions/warnings, not errors
+- **Profile-Aware**: Suggestions shown in all profiles for maximum helpfulness
+- **Actionable**: Clear guidance on how to implement best practices
+- **Production-Focused**: Addresses real workflow reliability concerns from actual broken workflows
+
+#### Test Coverage
+
+Added 8 new test cases covering:
+- alwaysOutputData suggestion for all HTTP Request nodes
+- responseFormat suggestion for API endpoint detection (various patterns)
+- responseFormat NOT suggested when already configured
+- URL protocol validation for expression-based URLs
+- Protocol warnings for missing http:// in expressions
+- No false positives when protocol is correctly included
+
+#### Technical Details
+
+**Files Modified:**
+- `src/services/enhanced-config-validator.ts` - Added `enhanceHttpRequestValidation()` implementation
+- `tests/unit/services/enhanced-config-validator.test.ts` - Added 8 comprehensive test cases
+
+**Validation Flow:**
+1. Check for alwaysOutputData suggestion (all HTTP Request nodes)
+2. Detect API endpoints by URL patterns
+3. Check for explicit responseFormat configuration
+4. Validate expression-based URLs for protocol issues
+
+#### Related
+
+- **Issue**: #361 - validate_node_operation: Missing critical HTTP Request node configuration checks
+- **Analysis**: Deep investigation with @agent-Explore and @agent-n8n-mcp-tester
+- **Workflows Analyzed**:
+  - SwjKJsJhe8OsYfBk (mixed syntax test)
+  - mBmkyj460i5rYTG4 (broken workflow)
+  - hQI9pby3nSFtk4TV (fixed workflow)
+
+Conceived by Romuald Członkowski - https://www.aiadvisors.pl/en
+
+---
+
 ### 🐛 Bug Fixes
 
 **Issue #360: Enhanced Warnings for If/Switch Node Connection Parameters**
diff --git a/data/nodes.db b/data/nodes.db
index b67f146..e22fcad 100644
Binary files a/data/nodes.db and b/data/nodes.db differ
diff --git a/package.json b/package.json
index 4a608cf..6ff5306 100644
--- a/package.json
+++ b/package.json
@@ -1,6 +1,6 @@
 {
   "name": "n8n-mcp",
-  "version": "2.22.1",
+  "version": "2.22.2",
   "description": "Integration between n8n workflow automation and Model Context Protocol (MCP)",
   "main": "dist/index.js",
   "types": "dist/index.d.ts",
diff --git a/src/services/enhanced-config-validator.ts b/src/services/enhanced-config-validator.ts
index beff9a2..6c652ce 100644
--- a/src/services/enhanced-config-validator.ts
+++ b/src/services/enhanced-config-validator.ts
@@ -401,7 +401,59 @@ export class EnhancedConfigValidator extends ConfigValidator {
     config: Record<string, any>,
     result: EnhancedValidationResult
   ): void {
-    // Examples removed - validation provides error messages and fixes instead
+    const url = String(config.url || '');
+    const options = config.options || {};
+
+    // 1. Suggest alwaysOutputData for better error handling (node-level property)
+    // Note: We can't check if it exists (it's node-level, not in parameters),
+    // but we can suggest it as a best practice
+    if (!result.suggestions.some(s => typeof s === 'string' && s.includes('alwaysOutputData'))) {
+      result.suggestions.push(
+        'Consider adding alwaysOutputData: true at node level (not in parameters) for better error handling. ' +
+        'This ensures the node produces output even when HTTP requests fail, allowing downstream error handling.'
+      );
+    }
+
+    // 2. Suggest responseFormat for API endpoints
+    const lowerUrl = url.toLowerCase();
+    const isApiEndpoint =
+      // Subdomain patterns (api.example.com)
+      /^https?:\/\/api\./i.test(url) ||
+      // Path patterns with word boundaries to prevent false positives like "therapist", "restaurant"
+      /\/api[\/\?]|\/api$/i.test(url) ||
+      /\/rest[\/\?]|\/rest$/i.test(url) ||
+      // Known API service domains
+      lowerUrl.includes('supabase.co') ||
+      lowerUrl.includes('firebase') ||
+      lowerUrl.includes('googleapis.com') ||
+      // Versioned API paths (e.g., example.com/v1, example.com/v2)
+      /\.com\/v\d+/i.test(url);
+
+    if (isApiEndpoint && !options.response?.response?.responseFormat) {
+      result.suggestions.push(
+        'API endpoints should explicitly set options.response.response.responseFormat to "json" or "text" ' +
+        'to prevent confusion about response parsing. Example: ' +
+        '{ "options": { "response": { "response": { "responseFormat": "json" } } } }'
+      );
+    }
+
+    // 3. Enhanced URL protocol validation for expressions
+    if (url && url.startsWith('=')) {
+      // Expression-based URL - check for common protocol issues
+      const expressionContent = url.slice(1); // Remove = prefix
+      const lowerExpression = expressionContent.toLowerCase();
+
+      // Check for missing protocol in expression (case-insensitive)
+      if (expressionContent.startsWith('www.') ||
+          (expressionContent.includes('{{') && !lowerExpression.includes('http'))) {
+        result.warnings.push({
+          type: 'invalid_value',
+          property: 'url',
+          message: 'URL expression appears to be missing http:// or https:// protocol',
+          suggestion: 'Include protocol in your expression. Example: ={{ "https://" + $json.domain + ".com" }}'
+        });
+      }
+    }
   }
   
   /**
diff --git a/tests/unit/services/enhanced-config-validator.test.ts b/tests/unit/services/enhanced-config-validator.test.ts
index 1998d46..64df123 100644
--- a/tests/unit/services/enhanced-config-validator.test.ts
+++ b/tests/unit/services/enhanced-config-validator.test.ts
@@ -802,4 +802,335 @@ describe('EnhancedConfigValidator', () => {
       expect(result.errors[0].property).toBe('test');
     });
   });
+
+  describe('enhanceHttpRequestValidation', () => {
+    it('should suggest alwaysOutputData for HTTP Request nodes', () => {
+      const nodeType = 'nodes-base.httpRequest';
+      const config = {
+        url: 'https://api.example.com/data',
+        method: 'GET'
+      };
+      const properties = [
+        { name: 'url', type: 'string', required: true },
+        { name: 'method', type: 'options', required: false }
+      ];
+
+      const result = EnhancedConfigValidator.validateWithMode(
+        nodeType,
+        config,
+        properties,
+        'operation',
+        'ai-friendly'
+      );
+
+      expect(result.valid).toBe(true);
+      expect(result.suggestions).toContainEqual(
+        expect.stringContaining('alwaysOutputData: true at node level')
+      );
+      expect(result.suggestions).toContainEqual(
+        expect.stringContaining('ensures the node produces output even when HTTP requests fail')
+      );
+    });
+
+    it('should suggest responseFormat for API endpoint URLs', () => {
+      const nodeType = 'nodes-base.httpRequest';
+      const config = {
+        url: 'https://api.example.com/data',
+        method: 'GET',
+        options: {} // Empty options, no responseFormat
+      };
+      const properties = [
+        { name: 'url', type: 'string', required: true },
+        { name: 'method', type: 'options', required: false },
+        { name: 'options', type: 'collection', required: false }
+      ];
+
+      const result = EnhancedConfigValidator.validateWithMode(
+        nodeType,
+        config,
+        properties,
+        'operation',
+        'ai-friendly'
+      );
+
+      expect(result.valid).toBe(true);
+      expect(result.suggestions).toContainEqual(
+        expect.stringContaining('responseFormat')
+      );
+      expect(result.suggestions).toContainEqual(
+        expect.stringContaining('options.response.response.responseFormat')
+      );
+    });
+
+    it('should suggest responseFormat for Supabase URLs', () => {
+      const nodeType = 'nodes-base.httpRequest';
+      const config = {
+        url: 'https://xxciwnthnnywanbplqwg.supabase.co/rest/v1/messages',
+        method: 'GET',
+        options: {}
+      };
+      const properties = [
+        { name: 'url', type: 'string', required: true }
+      ];
+
+      const result = EnhancedConfigValidator.validateWithMode(
+        nodeType,
+        config,
+        properties,
+        'operation',
+        'ai-friendly'
+      );
+
+      expect(result.suggestions).toContainEqual(
+        expect.stringContaining('responseFormat')
+      );
+    });
+
+    it('should NOT suggest responseFormat when already configured', () => {
+      const nodeType = 'nodes-base.httpRequest';
+      const config = {
+        url: 'https://api.example.com/data',
+        method: 'GET',
+        options: {
+          response: {
+            response: {
+              responseFormat: 'json'
+            }
+          }
+        }
+      };
+      const properties = [
+        { name: 'url', type: 'string', required: true },
+        { name: 'options', type: 'collection', required: false }
+      ];
+
+      const result = EnhancedConfigValidator.validateWithMode(
+        nodeType,
+        config,
+        properties,
+        'operation',
+        'ai-friendly'
+      );
+
+      const responseFormatSuggestion = result.suggestions.find(
+        (s: string) => s.includes('responseFormat')
+      );
+      expect(responseFormatSuggestion).toBeUndefined();
+    });
+
+    it('should warn about missing protocol in expression-based URLs', () => {
+      const nodeType = 'nodes-base.httpRequest';
+      const config = {
+        url: '=www.{{ $json.domain }}.com',
+        method: 'GET'
+      };
+      const properties = [
+        { name: 'url', type: 'string', required: true }
+      ];
+
+      const result = EnhancedConfigValidator.validateWithMode(
+        nodeType,
+        config,
+        properties,
+        'operation',
+        'ai-friendly'
+      );
+
+      expect(result.warnings).toContainEqual(
+        expect.objectContaining({
+          type: 'invalid_value',
+          property: 'url',
+          message: expect.stringContaining('missing http:// or https://')
+        })
+      );
+    });
+
+    it('should warn about missing protocol in expressions with template markers', () => {
+      const nodeType = 'nodes-base.httpRequest';
+      const config = {
+        url: '={{ $json.domain }}/api/data',
+        method: 'GET'
+      };
+      const properties = [
+        { name: 'url', type: 'string', required: true }
+      ];
+
+      const result = EnhancedConfigValidator.validateWithMode(
+        nodeType,
+        config,
+        properties,
+        'operation',
+        'ai-friendly'
+      );
+
+      expect(result.warnings).toContainEqual(
+        expect.objectContaining({
+          type: 'invalid_value',
+          property: 'url',
+          message: expect.stringContaining('missing http:// or https://')
+        })
+      );
+    });
+
+    it('should NOT warn when expression includes http protocol', () => {
+      const nodeType = 'nodes-base.httpRequest';
+      const config = {
+        url: '={{ "https://" + $json.domain + ".com" }}',
+        method: 'GET'
+      };
+      const properties = [
+        { name: 'url', type: 'string', required: true }
+      ];
+
+      const result = EnhancedConfigValidator.validateWithMode(
+        nodeType,
+        config,
+        properties,
+        'operation',
+        'ai-friendly'
+      );
+
+      const urlWarning = result.warnings.find(
+        (w: any) => w.property === 'url' && w.message.includes('protocol')
+      );
+      expect(urlWarning).toBeUndefined();
+    });
+
+    it('should NOT suggest responseFormat for non-API URLs', () => {
+      const nodeType = 'nodes-base.httpRequest';
+      const config = {
+        url: 'https://example.com/page.html',
+        method: 'GET',
+        options: {}
+      };
+      const properties = [
+        { name: 'url', type: 'string', required: true }
+      ];
+
+      const result = EnhancedConfigValidator.validateWithMode(
+        nodeType,
+        config,
+        properties,
+        'operation',
+        'ai-friendly'
+      );
+
+      const responseFormatSuggestion = result.suggestions.find(
+        (s: string) => s.includes('responseFormat')
+      );
+      expect(responseFormatSuggestion).toBeUndefined();
+    });
+
+    it('should detect missing protocol in expressions with uppercase HTTP', () => {
+      const nodeType = 'nodes-base.httpRequest';
+      const config = {
+        url: '={{ "HTTP://" + $json.domain + ".com" }}',
+        method: 'GET'
+      };
+      const properties = [
+        { name: 'url', type: 'string', required: true }
+      ];
+
+      const result = EnhancedConfigValidator.validateWithMode(
+        nodeType,
+        config,
+        properties,
+        'operation',
+        'ai-friendly'
+      );
+
+      // Should NOT warn because HTTP:// is present (case-insensitive)
+      expect(result.warnings).toHaveLength(0);
+    });
+
+    it('should NOT suggest responseFormat for false positive URLs', () => {
+      const nodeType = 'nodes-base.httpRequest';
+      const testUrls = [
+        'https://example.com/therapist-directory',
+        'https://restaurant-bookings.com/reserve',
+        'https://forest-management.org/data'
+      ];
+
+      testUrls.forEach(url => {
+        const config = {
+          url,
+          method: 'GET',
+          options: {}
+        };
+        const properties = [
+          { name: 'url', type: 'string', required: true }
+        ];
+
+        const result = EnhancedConfigValidator.validateWithMode(
+          nodeType,
+          config,
+          properties,
+          'operation',
+          'ai-friendly'
+        );
+
+        const responseFormatSuggestion = result.suggestions.find(
+          (s: string) => s.includes('responseFormat')
+        );
+        expect(responseFormatSuggestion).toBeUndefined();
+      });
+    });
+
+    it('should suggest responseFormat for case-insensitive API paths', () => {
+      const nodeType = 'nodes-base.httpRequest';
+      const testUrls = [
+        'https://example.com/API/users',
+        'https://example.com/Rest/data',
+        'https://example.com/REST/v1/items'
+      ];
+
+      testUrls.forEach(url => {
+        const config = {
+          url,
+          method: 'GET',
+          options: {}
+        };
+        const properties = [
+          { name: 'url', type: 'string', required: true }
+        ];
+
+        const result = EnhancedConfigValidator.validateWithMode(
+          nodeType,
+          config,
+          properties,
+          'operation',
+          'ai-friendly'
+        );
+
+        expect(result.suggestions).toContainEqual(
+          expect.stringContaining('responseFormat')
+        );
+      });
+    });
+
+    it('should handle null and undefined URLs gracefully', () => {
+      const nodeType = 'nodes-base.httpRequest';
+      const testConfigs = [
+        { url: null, method: 'GET' },
+        { url: undefined, method: 'GET' },
+        { url: '', method: 'GET' }
+      ];
+
+      testConfigs.forEach(config => {
+        const properties = [
+          { name: 'url', type: 'string', required: true }
+        ];
+
+        expect(() => {
+          EnhancedConfigValidator.validateWithMode(
+            nodeType,
+            config,
+            properties,
+            'operation',
+            'ai-friendly'
+          );
+        }).not.toThrow();
+      });
+    });
+  });
 });
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